ArticleResuscitation plus2026
The impact of head and thorax elevation on respiratory mechanics during cardiopulmonary resuscitation: a multi-model study.
Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The impact on ventilation of head and thorax elevation (HTE) and the use of an impedance threshold device (ITD) during cardiopulmonary resuscitation (CPR) remains poorly understood. The aim was to describe the impact on ventilation and absolute lung volumes of HTE vs. horizontal (FLAT) positions, with or without ITD use, across multiple cardiac arrest experimental models. Methods: This was a cross-over experimental trial conducted using three models: pigs, Thiel-embalmed cadavers, and thawed fresh-frozen cadavers. Two protocols were applied in a 1:1 randomized order: FLAT and HTE positions first, with or without ITD. Primary outcome was the calculation of absolute loss of lung volume (Vloss) below the functional residual capacity. Airway opening pressure (AOP) and respiratory system compliance (Crs) were also calculated, both assessed before CPR initiation. Linear mixed models were used for statistical analysis. Results: Eight pigs and eight cadavers (4 Thiel, 4 fresh-frozen) were included. In the linear mixed model, there was a significant difference for Vloss for FLAT vs. HTE ( Conclusions: In this multi-model study, HTE during CPR limits loss of lung volume below functional residual capacity.
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