Evidence map›Paper›PMID 42750951›Full record

ArticleFrontiers in oncology2026

ANP32A interacts with LDHA to modulate glycolysis and ferroptosis in hepatocellular carcinoma.

Bixia Chi, Zhi Cui, Xinyue Hou, Hongfang Ding, Linjun Li, Rui Ai, Yizhuang Yang, Yue Zhao, Liyan Wang, Juan Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bixia Chi *Department of Gastroenterology, The First Affiliated Hospital of Guilin Medical University, Guilin, China.
Zhi Cui *Department of Pain Treatment, PKUCare Luzhong Hospital, Zibo, China.
Xinyue HouDepartment of Pharmacy, Guilin Medical University, Guilin, China.
Hongfang DingFaculty of Basic Medicine, Guilin Medical University, Guilin, China.
Linjun LiDepartment of Pharmacy, Guilin Medical University, Guilin, China.
Rui AiDepartment of Pharmacy, Guilin Medical University, Guilin, China.
Yizhuang YangDepartment of Pharmacy, Guilin Medical University, Guilin, China.
Yue ZhaoDepartment of Pharmacy, Guilin Medical University, Guilin, China.
Liyan WangDepartment of Gastroenterology, The First Affiliated Hospital of Guilin Medical University, Guilin, China.
Juan WangFaculty of Basic Medicine, Guilin Medical University, Guilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acidic leucine-rich nuclear phosphoprotein 32A(ANP32A) is known to possess multi-functions and has been observed to exhibit different roles across various malignancies. Although the expression of ANP32A has been shown to correlate with metastatic spread and reduced survival in Hepatocellular carcinoma(HCC), the underlying mechanisms have not been fully elucidated. This study utilized univariate Cox regression, differential gene analysis, and WGCNA to identify ANP32A as closely associated with poor HCC prognosis. Our Co-IP results confirmed the interaction between ANP32A and LDHA. Additionally, silencing ANP32A inhibited HCC cell proliferation

Indexed as

cell proliferationferroptosisglycolysishepatocellular carcinoma (HCC)ubiquitination

Identifiers

PMID42750951
PMCPMC13579258

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.