Evidence map›Paper›PMID 42753249›Full record

Trial reportJMIR cardio2026

Improving Cardiometabolic Health in Adolescent Girls With Elevated Anxiety: Web-Based Multisite, Pilot, and Feasibility Randomized Controlled Trial.

Caitlin Edwards, Lisa Ranzenhofer, Jason Lavender, Lauren D Gulley, Stephen Aichele, Isabel Thorstad, Natalia Sanchez, Ruby Schrag, Zoe Sinkford, Jill Emerick and 7 more

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in JMIR cardio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Caitlin Edwards *Department of Human Development and Family Studies, College of Health and Human Services, Colorado State University, 410 W. Pitkin St, 1570 Campus Delivery, Fort Collins, CO, 80523, United States, 1 970-491-3217.ORCID http://orcid.org/0000-0001-7576-0483
Lisa Ranzenhofer *Department of Psychiatry, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, United States.ORCID http://orcid.org/0000-0002-7199-6998
Jason Lavender *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0000-0001-9853-2280
Lauren D Gulley *Endocrinology, Department of Pediatrics, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora, CO, United States.ORCID http://orcid.org/0000-0002-3868-8096
Stephen Aichele *Department of Human Development and Family Studies, College of Health and Human Services, Colorado State University, 410 W. Pitkin St, 1570 Campus Delivery, Fort Collins, CO, 80523, United States, 1 970-491-3217.ORCID http://orcid.org/0000-0002-3397-7921
Isabel Thorstad *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0009-0005-7710-0186
Natalia Sanchez *Department of Human Development and Family Studies, College of Health and Human Services, Colorado State University, 410 W. Pitkin St, 1570 Campus Delivery, Fort Collins, CO, 80523, United States, 1 970-491-3217.ORCID http://orcid.org/0000-0001-7929-4029
Ruby Schrag *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0009-0001-5691-4659
Zoe Sinkford *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0009-0008-4359-4271
Jill Emerick *Department of Pediatrics, Uniformed Services University, Bethesda, MD, United States.ORCID http://orcid.org/0000-0002-1839-8980
Victoria Thomas *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0009-0003-6480-9394
Thomas Arnold *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0009-0003-9665-4518
Jami Young *Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID http://orcid.org/0000-0002-7488-5097
Denise Wilfley *Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, United States.ORCID http://orcid.org/0000-0002-3599-8689
Mark Haigney *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0000-0001-6449-4386
Lauren Shomaker *Department of Human Development and Family Studies, College of Health and Human Services, Colorado State University, 410 W. Pitkin St, 1570 Campus Delivery, Fort Collins, CO, 80523, United States, 1 970-491-3217.ORCID http://orcid.org/0000-0002-6129-8707
Marian Tanofsky-Kraff *Department of Medicine, Military and Cardiovascular Outcomes Research (MiCOR), Uniformed Services University of the Health Sciences, Bethesda, MD, United States.ORCID http://orcid.org/0000-0003-3871-2233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anxiety is common in adolescents with elevated BMI (kg/m Objective: This pilot study primarily aimed to assess the feasibility and acceptability of 2 virtual group psychological interventions, interpersonal psychotherapy (IPT) and cognitive behavioral therapy (CBT), in adolescent girls with elevated anxiety and above-average weight. Secondary aims were to describe changes in anxiety, eating behavior, and cardiometabolic health indices. Methods: This 2-site, 2-year, pilot and feasibility randomized controlled trial enrolled 12- to 17-year-old girls with elevated anxiety symptoms (State-Trait Anxiety Inventory for Children total score ≥32) and above-average weight (BMI ≥75th percentile for age and sex), who were in good general health and not concurrently receiving therapy or medication treatment. Girls were randomly assigned to 1 of 2 web-based arms: 12-week, psychologist-led, group IPT or CBT. In both arms, groups of 5-7 adolescents met for 90 minutes on secure Zoom (Zoom Communications, Inc) once per week. Anxiety, disinhibited eating, BMI indices, blood pressure, lipids, hemoglobin A Results: Of 47 eligible adolescents, 40 (85%) enrolled. Enrollment of the total sample (n=40) was completed in 7 months. Retention was 85% (n=17) in IPT and 100% (n=20) in CBT at 12-week follow-up. Protocol adherence exceeded 96% for all intervals. Missing data varied, with higher rates for phlebotomy (up to 30%). Acceptability ratings were above-average for likability (mean 3.03, SD 1.14) and credibility (mean 3.26, SD 0.75; 0-4 scale with 4=Highest) across arms. Most adolescents received ≥80% intervention dosage (IPT: 90%, CBT: 95%). Expert fidelity ratings of IPT were 78% (SD 11%) and CBT were 94% (SD 9%). From baseline to 1-year, IPT demonstrated improvements in general anxiety (95% CI -8.95 to -1.40), social anxiety (95% CI -12.37 to -1.88), and HbA Conclusions: This pilot and feasibility trial provided initial support for the feasibility of recruitment and retention and acceptability of web-based group IPT and CBT, as well as yielded areas for optimizing protocol feasibility and intervention fidelity. These preliminary results inform the planning of larger-scale efficacy trials with powered samples to assess effects on BMI and cardiometabolic health indicators among adolescents with elevated anxiety and above-average weight.

Indexed as

AnxietyCognitive Behavioral TherapyAdolescentBody Mass IndexChildFeasibility StudiesFemaleHumansPilot Projectsadolescentsanxietycardiometabolic healthcognitive behavioral therapyeating behaviorsfeasibilityinterpersonal psychotherapypilot trial

Identifiers

PMID42753249
PMCPMC13585365

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.