Evidence map›Paper›PMID 42756748›Full record

ArticleInternational journal of endocrinology2026

Alireza Raeisi, Farhad Koohpeyma, Roozbeh Kiani, Somayeh Igder, Amir Maleksabet, Nima Rahimikashkooli, Narges Rezaei, Mesbah Shams, Sanaz Dastghaib

Abstract read
In one paragraph

Article in International journal of endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alireza RaeisiEndocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0009-0006-5134-4200
Farhad KoohpeymaEndocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0000-0001-6729-7732
Roozbeh KianiAutophagy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0009-0007-9022-8939
Somayeh IgderHyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, ajums.ac.ir.ORCID https://orcid.org/0000-0002-3096-2660
Amir MaleksabetDepartment of Medical Biotechnology, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran, mazums.ac.ir.ORCID https://orcid.org/0000-0001-9248-9648
Nima RahimikashkooliInternal Medicine Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0000-0001-6850-4983
Narges RezaeiHematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0009-0000-1848-9850
Mesbah ShamsEndocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0000-0002-3210-0159
Sanaz DastghaibEndocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.ORCID https://orcid.org/0000-0001-8553-9221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Endoplasmic reticulum stress (ERS) plays a pivotal role in the development of diabetes-induced liver damage. Under elevated ERS, the unfolded protein response (UPR) balances cellular survival and death. There may be a preventive effect of herbal extracts against problems associated with diabetes. In this study, the effects of a hydroalcoholic extract from Methods: There were five groups of rats, each including six rats. A 60 mg/kg intraperitoneal injection of streptozotocin (STZ) was used to cause diabetes. Every day, 1 mL of normal saline was given to the control groups, who were normal and diabetic. For 28 days, three diabetic groups were given oral gavage doses of 250/500 mg/kg of Results: Compared to the diabetic groups, the treated groups exhibited a significant decrease in oxidative stress, inflammatory markers, liver enzymes, blood glucose, and increased antioxidant capacity. They significantly reduced mRNA levels of proapoptotic markers ( Conclusion:

Indexed as

antioxidantdiabetesDorema aucherigene expressionliver enzymesoxidative stress

Identifiers

PMID42756748
PMCPMC13583441

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.