ReviewDiscover nano2026
Ultrasound triggered microbubbles enhance the diagnosis and therapy of colorectal cancer.
Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
As an emerging integrated diagnostic and therapeutic platform, ultrasound-triggered microbubbles (UTMBs) have demonstrated significant potential in the treatment of colorectal cancer (CRC). This article introduces the different types of UTMBs, including micron-sized bubbles, nanobubbles, and nanodroplets) and describes their respective structural characteristics. These characteristics directly influence the behavior and function of UTMBs in vivo. The mechanisms underlying UTMB-mediated tumor therapy are systematically summarized, including physical effects (such as cavitation, acoustic streaming, and thermal effects), modulation of the tumor microenvironment (TME), and synergistic interactions with therapeutic agents. In addition, the diagnostic applications of UTMBs in CRC are discussed, including contrast-enhanced ultrasound (CEUS) imaging, molecular marker detection, and monitoring of treatment response. The potential applications of UTMBs in chemotherapy sensitization, immunotherapy synergy, and gene therapy are further highlighted. Finally, the challenges and limitations of UTMBs in CRC diagnosis and treatment are analyzed, and future development directions are outlined. This review aims to provide a comprehensive reference and guidance for further research and clinical translation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.