Evidence map›Paper›PMID 42758638›Full record

ArticleThe Journal of general virology2026

Cellular PrP

Jesse Cole, Erin E McNulty, Amy V Nalls, Nathaniel D Denkers, Gary L Mason, Candace K Mathiason

Abstract read
In one paragraph

Article in The Journal of general virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jesse ColeDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Erin E McNultyDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Amy V NallsDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Nathaniel D DenkersDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Gary L MasonDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Candace K MathiasonDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.

Funding

Zoonotic potential of CWD and influence of environmental contamination on prion propagationP01AI077774 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CLAUDIO SOTO · 2008 to 2026
$36.1M
Detection and Characterization of Blood-borne PrionsR01AI112956 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2014 to 2024
$4.6M
Chronic Wasting Disease VaccinesR01AI156037 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2021 to 2025
$3.5M
CSU Infectious Disease Research and Response Training ProgramT32AI162691 · NIAID · COLORADO STATE UNIVERSITY · PI DEAN, GREGG A · 2021 to 2025
$2.1M
Dual-Degree Medical Scientist Training Program for VeterinariansT32GM136628 · NIGMS · COLORADO STATE UNIVERSITY · PI ANNE C AVERY, Daniel Patrick Regan · 2020 to 2026
$1.9M
NIAID NIH HHS P01 AI077774NIAID NIH HHS R01 AI112956NIAID NIH HHS R01 AI156037NIAID NIH HHS T32 AI162691NIGMS NIH HHS T32 GM136628
6 · The paper itself

Abstract

Vertical transmission has been identified as a viable route of transmission in the spread of chronic wasting disease (CWD), yet demonstration of trafficking mechanism(s) at the maternal-foetal interface has been limited. Conventional assays, including immunohistochemistry (IHC), Western blot and ELISA, often fail to detect low concentrations of the aberrant prion protein (PrP

Indexed as

DeerInfectious Disease Transmission, VerticalPlacentaPrion ProteinsPrionsWasting Disease, ChronicAnimalsFemaleImmunohistochemistryPregnancyUterusPrion ProteinsPrionsamplification-IHC (AMP-IHC)CWDprionsuterine glandvertical transmission

Identifiers

PMID42758638
PMCPMC13588596

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.