Evidence map›Paper›PMID 42758736›Full record

ArticleEuropean stroke journal2026

European Stroke Organisation survey on reperfusion therapy practices.

Michele Marvardi, Ronen Leker, Sumanjit Gill, Volker Pütz, Theresa Ullberg, Pierre Seners, Maria Hernández-Pérez, Jonathan M Coutinho, Kristian Karlović, Klaudia Soltesova and 2 more

Abstract read
In one paragraph

Article in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michele MarvardiDepartment of Emergency and Emergency Medicine, Gubbio-Gualdo Tadino Hospital, USL Umbria 1, Italy.
Ronen LekerDepartment of Neurology, Hadassah-Hebrew University Medical Center, Ein Kerem Campus, Jerusalem, Israel.
Sumanjit GillUniversity College London (UCL) Queen Square Institute of Neurology, London, United Kingdom.
Volker PützDepartment of Neurology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Theresa UllbergDepartment of Neurology, Skane University Hospital, Lund University, Lund, Sweden.
Pierre SenersNeurology Department, Rothschild Foundation Hospital, Paris, France.
Maria Hernández-PérezStroke Unit, Neurosciences Department, Germans Trias i Pujol University Hospital, Universitat Autònoma de Barcelona, Badalona, Spain.
Jonathan M CoutinhoDepartment of Emergency and Emergency Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Kristian KarlovićRadiology Department, University Clinical Hospital of Mostar, and School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.
Klaudia SoltesovaDepartment of Neurology, Louis Pasteur University Hospital Košice, Mostar, Slovakia.
Julian BöselDepartment of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
Valeria CasoNeurology-Stroke Unit, Saronno Hospital, ASST Valle Olona, Saronno, Italy.ORCID 0000-0002-2020-8891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRapid reperfusion remains critical in acute ischaemic stroke, yet substantial prehospital delays persist. Clinicians across Europe widely use stroke code protocols and reperfusion strategies. However, clinicians lack routine data in clinical practice on prehospital triage, workflow organisation and performance monitoring. PATIENTS AND

methodsThe European Stroke Organisation (ESO) Endovascular Task Force conducted a multinational, cross-sectional, scenario-based e-survey. The survey targeted emergency medical services (EMS), primary stroke centres (PSCs) and comprehensive stroke centres (CSCs). It evaluated how teams assess patients in the prehospital setting, select transport methods, organise workflows, monitor time intervals and audit practices in European stroke networks.

resultsA total of 296 responses from 43 European countries were analysed. Most originated from urban settings and CSCs. Stroke code activation and hospital pre-notification occurred in over 90% of EMS scenarios. Among EMS respondents, 80.4% transported patients with mild-to-moderate symptoms to the nearest hospital capable of intravenous thrombolysis. However, in cases with suspected LVO, transport destinations varied: 49.0% were transported to PSCs, 31.4% were transported to CSCs and 19.6% were transported to the nearest hospital regardless of reperfusion capability. Monitoring of key time intervals was inconsistent. Emergency medical services did not monitor call-to-hospital arrival times in 25.5% of services. Only 46.7% of PSCs and 53.5% of CSCs routinely monitored EMS arrival times. At the PSC level, 25.0% did not monitor door-in-door-out time, and 30.0% reported dedicated stroke teams were unavailable during nights and weekends. At the CSC level, admission-to-reperfusion time was monitored in 90.8% of centres, but only 28.6% audited delays when they occurred. Additionally, 42.2% of CSCs reported no on-site neuro-interventional team availability during nights or weekends. Fewer than two-thirds of EMS and PSC services, and about one-third of CSCs, reported regular audit activity.

conclusionsAlthough stroke code activation and pre-notification are widely implemented across Europe, this survey identifies important gaps in systematic time monitoring and audit practices, alongside a lack of continuous (24/7) specialist coverage across the stroke care pathway. Key performance metrics are frequently not tracked, and audit-driven quality improvement remains limited.

Indexed as

Emergency Medical ServicesReperfusionStrokeThrombolytic TherapyCross-Sectional StudiesEuropeHumansSurveys and Questionnairesacute strokeprehospital pathwaythrombectomythrombolysis

Identifiers

PMID42758736
PMCPMC13588096

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.