Evidence map›Paper›PMID 42761446›Full record

ArticleiScience2026

Gypenosides ameliorate polycystic ovary syndrome via gut microbiota modulation: An integrated gut microbiome and ovarian transcriptome study.

Shaorong Li, Jiangfan Wan, Zhijie Liang, Jinzhuai Li, Hongmian Jiang, Lifeng Luo, Yingying Li, Shuying Luo, Huali Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shaorong LiThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Jiangfan WanThe Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning 530000, China.
Zhijie LiangThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Jinzhuai LiState Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China.
Hongmian JiangThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Lifeng LuoThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Yingying LiThe Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning 530000, China.
Shuying LuoThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.
Huali HuangThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning 530000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder with complex metabolic and reproductive manifestations. Gut microbiota dysbiosis has emerged as a key factor in PCOS, yet the causal role of microbiota-targeted interventions remains to be fully defined. In a letrozole-induced rat model, we show that gypenosides (GPs)-bioactive saponins from

Indexed as

GPsgut microbiotagypenosidesinflammatory responseoxidative stressPCOSpolycystic ovary syndrometranscriptomics

Identifiers

PMID42761446
PMCPMC13586521

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.