ReviewOdontology2026
Therapeutic potential of Vaccinium species in the prevention and management of erosion and dental caries: a systematic review.
Review in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
According to the World Health Organization, oral diseases affect approximately 45% of the global population, constituting a major health concern. This systematic review aimed to analyze scientific literature on the species, compounds, uses, and applications of the genus Vaccinium in dentistry, focusing on its potential as therapeutic agents. The review was conducted in accordance with PRISMA 2020 guidelines. A comprehensive search was performed in PubMed, Web of Science, Scopus, and Embase up to December 2025, using predefined keywords related to Vaccinium species and dental caries. Eligible studies included in vitro and clinical trials investigating Vaccinium-based products for tooth decay, while reviews and studies lacking methodological detail were excluded. Risk of bias was assessed using the QUIN tool for in vitro studies and the Cochrane RoB 2 tool for randomized clinical trials. Data were extracted independently by three reviewers and synthesized narratively due to heterogeneity in study designs and outcomes. A total of 42 studies published between 1998 and 2025 were included. Results highlight the anticaries properties of Vaccinium species, particularly V. macrocarpon and V. corymbosum demonstrate promising anticariogenic properties. In vitro studies indicate that V. macrocarpon can remineralize enamel and dentin, while V. macrocarpon and V. vitis-idaea can reduce dental biofilm and combat oral pathogens. Despite limitations, the Vaccinium genus emerges as a promising candidate for managing oral health conditions. Further rigorous clinical trials are required to validate these findings. This review received no external funding, and the protocol for this systematic review was registered in OSF (10.17605/OSF.IO/XU3GE).
Indexed as
Identifiers
42763376What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.