ArticleAnalytical and bioanalytical chemistry2026
Light-guided SERS-active micromotor clusters for on-site detection of microorganisms.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Surface-enhanced Raman spectroscopy (SERS) provides ultrasensitive molecular fingerprinting, but conventional static SERS substrates are often limited by inefficient analyte capture and poor spatial controllability. Herein, we report a light-driven micromotor SERS detector based on silver-coated polystyrene microspheres (Ag@PS) for active, localized, and rapid biochemical sensing. The Ag@PS micromotors were fabricated through an electroless silver-plating strategy, forming a dense nanoparticle-like silver shell that provides abundant plasmonic hotspots for SERS enhancement. Under light irradiation, the micromotors exhibited reversible "on-off" locomotion, positive phototaxis, and pronounced light-induced clustering. The micromotors reached an average velocity of approximately 6 μm s⁻
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