Evidence map›Paper›PMID 42768238›Full record

ReviewAAPS PharmSciTech2026

Terpesomes as Advanced Nanocarriers for Enhanced Drug Delivery: Formulation Strategies, Mechanistic Insights, and Therapeutic Applications.

Anroop B Nair, Mohamed A Morsy, Ahmed M Agiba, Rofida Albash

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anroop B NairDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Hofuf, Saudi Arabia.ORCID http://orcid.org/0000-0003-2850-8669
Mohamed A MorsyDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Hofuf, Saudi Arabia. momorsy@kfu.edu.sa.ORCID http://orcid.org/0000-0002-6752-9094
Ahmed M AgibaR&D Directorate, Multicare Egypt for Pharmaceutical Industries S.A.E., Industrial Area, New Cairo 3, Cairo, 11511, New Cairo 3, Egypt.ORCID http://orcid.org/0000-0003-3635-9093
Rofida AlbashDepartment of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), Giza, 12585, Egypt.ORCID http://orcid.org/0000-0003-1775-264X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Terpenes have a low potential for irritation and are classified as Generally Recognized as Safe (GRAS) chemicals. Terpenes possess favorable biological properties that support their use in drug delivery. Some terpenes and essential oils have been encapsulated in nanostructured systems called terpesomes to overcome their chemical instability. Compared to conventional vesicles, terpesomes are new vesicular structures that showed greater membrane penetration. The capacity of terpesomes to increase permeability across membranes while decreasing systemic absorption is one of their main benefits. Terpesomes enhance drug permeation by improving membrane interaction and increasing drug transport across biological barriers. The structure, characterization, penetration processes, and applications of terpesomes are all addressed in this review. Overall, this review highlights that the enhanced penetration capability of terpesomes makes them promising lipid vesicular carriers for a wide range of pharmaceutical applications.

Indexed as

Drug CarriersNanoparticlesNanostructuresTerpenesAdministration, CutaneousAnimalsChemistry, PharmaceuticalDrug CompoundingDrug Delivery SystemsHumansLipidsOils, VolatilePermeabilitySkin AbsorptionDrug CarriersLipidsOils, VolatileTerpenesnanovesiclespenetration enhancementterpenesterpesomestransdermal delivery

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.