ArticleArchiv der Pharmazie2026
Novel Diterpenoids From Salvia rosmarinus Reveal a Compound With Antiproliferative and Antioxidant Activities.
Article in Archiv der Pharmazie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
Abstract
Four previously undescribed diterpenoids (1-4) were isolated from the leaves of Salvia rosmarinus and characterized as 18-hydroxycarnosol (1), 18-acetoxyrosmanol (2), 18-acetoxycarnosol (3), and 18-acetoxy-7-O-methylrosmanol (4). Furthermore, nine known compounds, including carnosol (5), rosmanol (6), 7-O-methylacacetin (7), salvigenin (8), hispidulin (9), cirsimaritin (10), (1S,4S)-p-menth-2-ene-1,4-diol (11), 3,4,5-trimethoxycinnamyl alcohol (12), and vanillic acid (13) were also isolated. The structure of the new compounds was established primarily through the analysis of 1D and 2D nuclear magnetic resonance (NMR) experiments and high-resolution mass spectrometry by direct analysis in real time technique (HRMS DART). The absolute configuration of 1 and 2 was established by DP4+ analysis and comparison between experimental and theoretical electronic circular dichroism (ECD) spectra. The antiproliferative activity was evaluated against a panel of cancer cell lines and one normal cell line. Compounds 1 and 5 exhibited IC
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