ArticleFrontiers in oncology2026
Fibroblast-derived gremlin-1 Is associated with ovarian cancer-cell phenotypes in co-culture models.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Cancer-associated fibroblasts (CAFs) can modify ovarian cancer-cell behavior through paracrine signals, but the contribution of CAF-derived Gremlin-1 remains incompletely defined. Methods: We compared stage IV and stage I ovarian-cancer transcriptomes in GSE9891, performed functional-enrichment analyses of differentially expressed genes, and interrogated CSIOVDB and KM Plotter for Results: GSE9891 DEGs were enriched in ECM-related processes. CSIOVDB associated higher Conclusion: CAF
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