Evidence map›Paper›PMID 42769119›Full record

ReviewJournal of inflammation research2026

Multi-Omics Insights into Chronic Rhinosinusitis with Nasal Polyps: A Review of Lipidomics, Proteomics, and Transcriptomics.

Shuting Wang, Kunpeng Ma, Li Sun, Ping Li, Limin Ma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuting WangDepartment of Otorhinolaryngology, Affiliated Hospital of Shandong Second Medical University, Weifang, 261041, People's Republic of China.ORCID 0009-0002-8146-0940
Kunpeng MaDepartment of Otorhinolaryngology, Affiliated Hospital of Shandong Second Medical University, Weifang, 261041, People's Republic of China.ORCID 0000-0001-6833-8583
Li SunDepartment of Otorhinolaryngology, Weifang Municipal Government Hospital, Weifang, 261041, People's Republic of China.
Ping LiDepartment of Otorhinolaryngology, Affiliated Hospital of Shandong Second Medical University, Weifang, 261041, People's Republic of China.
Limin MaDepartment of Plastic Surgery, Plastic Surgery Hospital Affiliated to Shandong Second Medical University, Weifang, 261041, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review summarizes recent advances in multi-omics research on chronic rhinosinusitis with nasal polyps (CRSwNP), focusing on lipidomics, proteomics, and transcriptomics. CRSwNP is a highly heterogeneous disease characterized by persistent inflammation, epithelial barrier dysfunction, and tissue remodeling, with high recurrence and variable treatment responses. Current studies are mostly limited to single-omics analyses, and few achieve systematic cross-layer integration. This review integrates evidence from three omics layers to construct a continuous pathological network, identify stable and translatable biomarkers, and support stratified management and precision therapy.

Indexed as

chronic rhinosinusitis with nasal polyps(CRSwNP)molecular mechanismsmulti-omicsprecision medicine

Identifiers

PMID42769119
PMCPMC13590418

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.