ArticleAmerican journal of translational research2026
Effects of endoscopic transnasal orbital decompression on anterior segment ocular blood flow and clinical outcome in thyroid-associated ophthalmopathy: a retrospective study.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroid-associated ophthalmopathy (TAO) is characterized by orbital inflammation and elevated intraorbital pressure, which may compromise anterior segment microcirculation. While endoscopic transnasal orbital decompression (ETOD) effectively alleviates proptosis and improves vision, its effect on microcirculation remains underexplored.
objectiveThis study aimed to evaluate the effect of ETOD on anterior segment microcirculation in TAO using SS-OCTA and to correlate these changes with clinical outcome.
methodsThis retrospective study included 45 TAO patients undergoing ETOD and 45 matched healthy controls. SS-OCTA measures (superficial, deep, and small vessel density; blood flow area) and clinical measures (exophthalmos, intraocular pressure, best-corrected visual acuity) were assessed preoperatively and 3 months postoperatively.
resultsPreoperatively, SVD was significantly higher in TAO patients than in healthy controls (50.63 ± 1.98% vs. 48.53 ± 2.78%, P < 0.001), whereas DVD showed no significant difference (47.93 ± 1.59% vs. 47.30 ± 2.57%, P = 0.169). In contrast, BFA was significantly lower (2.07 ± 0.31 vs. 2.49 ± 0.27 mm
conclusionsETOD effectively reduced exophthalmos and IOP and restored anterior segment hemodynamics by decreasing pathologically elevated vessel densities toward normal levels. SS-OCTA provides a valuable noninvasive tool for monitoring microcirculatory changes after orbital decompression in TAO.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.