ArticleBiomedical optics express2026
Neurointerventional optical coherence tomography using a piezo-driven microprobe.
Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravascular optical coherence tomography (IV-OCT) is a promising tool for cerebrovascular imaging, but its clinical use remains limited by two unresolved problems: proximal-scanning catheters suffer from non-uniform rotational distortion (NURD) in tortuous vessels, whereas distal-scanning micro-electromagnetic motors are hampered by wire artifacts that block full 360° visualization. Here, we present a piezoelectric-driven micro-optical probe for imaging within complex cerebral vasculature. Using an integrated structure-function design, the probe is compact, measuring 0.55 mm in diameter and 4 mm in length. A slanted-groove configuration converts longitudinal vibration into torsional vibration, enabling wire-artifact-free scanning with a single-phase drive circuit. In a full-scale human cerebrovascular phantom, the probe navigated the middle cerebral artery and rotated uniformly at speeds up to 58 revolutions per second. Imaging of metal-tube phantoms, magnolia-leaf microveins, vascular stents, ex vivo porcine vessels, and human atherosclerotic plaques confirmed that the probe can resolve microvascular architecture, stent geometry, lipid deposits, and fibrotic tissue, with the OCT findings supported by histological analysis. Together, these results indicate that the proposed piezoelectric-driven microprobe offers a viable route toward precise intravascular optical imaging for cerebrovascular interventions.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.