Evidence map›Paper›PMID 42770085›Full record

ArticleRSC advances2026

Novel glutaminase-free l-asparaginase from

Thanapon Charoenwongpaiboon, Karan Wangpaiboon, Yanisa Srichompoo, Praphasri Septham, Phatchanat Klaihmon, Sujittra Khampang, Surapol Issaragrisil, Chanchao Lorthongpanich

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thanapon CharoenwongpaiboonDepartment of Chemistry, Faculty of Science, Silpakorn University Nakhon Pathom 73000 Thailand charoenwongpaib_t@su.ac.th.ORCID https://orcid.org/0000-0001-9322-0261
Karan WangpaiboonCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University Bangkok 10330 Thailand.
Yanisa SrichompooDepartment of Chemistry, Faculty of Science, Silpakorn University Nakhon Pathom 73000 Thailand charoenwongpaib_t@su.ac.th.
Praphasri SepthamSiriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok 10700 Thailand Chanchao.lor@mahidol.ac.th.
Phatchanat KlaihmonSiriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok 10700 Thailand Chanchao.lor@mahidol.ac.th.
Sujittra KhampangSiriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok 10700 Thailand Chanchao.lor@mahidol.ac.th.
Surapol IssaragrisilSiriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok 10700 Thailand Chanchao.lor@mahidol.ac.th.
Chanchao LorthongpanichSiriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok 10700 Thailand Chanchao.lor@mahidol.ac.th.ORCID https://orcid.org/0000-0003-2206-7065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-Asparaginase is an essential chemotherapeutic enzyme used to treat acute lymphoblastic leukaemia and certain lymphoid malignancies; however, its clinical use can be limited by adverse effects linked to immunogenicity and undesirable l-glutaminase activity. In this study, a novel glutaminase-free l-asparaginase from

Identifiers

PMID42770085
PMCPMC13592429

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.