Identification and gene expression profiling of toll genes in the potato psyllid (Bactericera cockerelli) in response to 'Candidatus liberibacter solanacearum'.

Md Tafim Hossain Hrithik, Julien Levy, Taylor Hubbs, Cecilia Tamborindeguy

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Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Md Tafim Hossain HrithikDepartment of Entomology, Texas A&M University, TAMU 2475, College Station, TX, 77843, USA.

Julien LevyDepartment of Horticultural Sciences, Texas A&M University, College Station, TAMU, TX, 2133, 77843, USA.

Taylor HubbsDepartment of Horticultural Sciences, Texas A&M University, College Station, TAMU, TX, 2133, 77843, USA.

Cecilia TamborindeguyDepartment of Entomology, Texas A&M University, TAMU 2475, College Station, TX, 77843, USA. ctamborindeguy@tamu.edu.ORCID http://orcid.org/0000-0002-0933-5785

Funding

National Institute of Food and Agriculture Multistate Hatch (Project #: 7755-1; accession #: 7003972)National Institute of Food and Agriculture TEX0-9381-2 (accession number 7005355)Texas A&M University Departmetn of Entomology Herb Dean'40 Endowed scholarshipTexas A&M Universtiy COALS Graduate Student Fellowship

6 · The paper itself

Abstract

backgroundThe Toll signaling pathway is a key component of insect innate immunity, yet its role in hemipteran vectors and their interactions with plant pathogens remains poorly understood. The potato psyllid (Bactericera cockerelli), an important agricultural pest in the USA, transmits two haplotypes of 'Candidatus Liberibacter solanacearum' (LsoA and LsoB) that cause severe diseases in solanaceous crops. METHODS AND

resultsWe characterized Toll pathway components in the B. cockerelli genome and examined their transcriptional responses during pathogen acquisition. Six Toll receptors and ten pathway-associated genes were identified in the psyllid genome. Gene expression was evaluated using RT-qPCR following exposure to the entomopathogenic fungus Beauveria bassiana (Bb-490) and infection with Lso haplotypes. The transcription of five Toll receptors was significantly induced in response to B. bassiana, indicating their potential role in antifungal defense. In contrast, Lso infection elicited haplotype-specific transcriptional responses: two Toll receptors (Toll like-1 and Toll-7) were up-regulated during LsoB acquisition, whereas only Toll-7 responded to LsoA. In addition, Spätzle-3 was induced by LsoB, while Spätzle was induced by LsoA. Persistent Lso infection did not significantly alter the transcriptional expression of Toll receptors.

conclusionsThese findings provide new insights into immune regulation in B. cockerelli and highlight the potential of targeting Toll-mediated responses and fungal biocontrol strategies for sustainable disease management.

Indexed as

HemipteraLiberibacterToll-Like ReceptorsAnimalsGene Expression ProfilingImmunity, InnateInsect ProteinsPlant DiseasesRhizobiaceaeSignal TransductionSolanum tuberosumInsect ProteinsToll-Like ReceptorsBactericera cockerelliCandidatus Liberibacter solanacearumGene expressionToll pathway

Identifiers

PMID42771278

DOI10.1007/s11033-026-12777-9

PMCPMC13597544

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.