Evidence map›Paper›PMID 42771719›Full record

ArticleRevista medica del Instituto Mexicano del Seguro Social2026

[Sleep disorders associated with montelukast in children with respiratory allergy].

Eduardo Amezola-Herrera, Lucy Vania Galindo-Pacheco, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista, Alejandro Moctezuma-Paz, Alma Patricia González

Abstract readEnglish Abstract
In one paragraph

Article in Revista medica del Instituto Mexicano del Seguro Social, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eduardo Amezola-HerreraInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.ORCID 0009-0008-5606-3306
Lucy Vania Galindo-PachecoInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No 48, Departamento de Alergia e Inmunología Pediátrica. León, Guanajuato, México.ORCID 0000-0002-6522-1707
Gloria Patricia Sosa-BustamanteInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.ORCID 0000-0002-8460-4965
Carlos Paque-BautistaInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.ORCID 0000-0002-2658-0491
Alejandro Moctezuma-PazInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Coordinación de Investigación en Salud, División de Investigación Clínica. Ciudad de México, México.ORCID 0000-0003-4015-8040
Alma Patricia GonzálezInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Gineco Pediatría No 48, Dirección de Educación e Investigación en Salud. León, Guanajuato, México.ORCID 0000-0002-3401-7519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asthma and allergic rhinitis are the most common respiratory allergic disorders in the Mexican population. Montelukast is a leukotriene receptor antagonist that has been widely used in these conditions. An association has been documented with the onset and modification of multiple sleep disorders, as well as other neuropsychiatric alterations in pediatric population. Objective: To analyze the association between montelukast and sleep disorders in children with respiratory allergies. Material and methods: A prospective and analytical cohort study was conducted. Patients aged 5 to 17 years diagnosed with asthma and allergic rhinitis were recruited from a third-level hospital. They were divided into 2 groups: a montelukast user group and a control group. Patients who withdrew their consent or did not complete the questionnaires were excluded. Results: 120 children were analyzed, 60 children using montelukast and 60 not using it. The median age was 9 and 10 years, respectively. Five (4.17%) of the children had asthma as their primary diagnosis, 60 (50%) had allergic rhinitis, and 55 (45.83%) had both asthma and allergic rhinitis. Among the children taking montelukast, 46 (73.02%) had sleep disorders, compared to 17 (14.17%) of those not taking montelukast. The association showed an odds ratio (OR) of 8.31, p < 0.0001. Conclusion: Montelukast use was associated with the presence of sleep disorders in the studied population.

Indexed as

AcetatesAnti-Asthmatic AgentsAsthmaLeukotriene AntagonistsQuinolinesRhinitis, AllergicSleep Wake DisordersAdolescentChildChild, PreschoolCyclopropanesFemaleHumansMaleProspective StudiesSulfidesAcetatesAnti-Asthmatic AgentsCyclopropanesLeukotriene AntagonistsmontelukastQuinolinesSulfidesAntagonistas de LeucotrienosAsmaAsthmaLeukotriene AntagonistsRhinitisRinitisSleep DisordersTrastornos del Sueño

Identifiers

PMID42771719
PMCPMC13614669

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.