Evidence map›Paper›PMID 42774444›Full record

ArticleInternational journal of cardiology. Heart & vasculature2026

Association between coronary vasomotor dysfunction and autoimmune disease in patients undergoing invasive coronary function testing.

Nida Latif, Yukang Zeng, Spyridon Kostantinis, Margaret Furman, Attila Feher, Monique Hinchcliff, Natasha Cigarroa, Guangyu Tong, Steffne J Kunnirickal, Natalija Odanovic and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nida LatifSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.
Yukang ZengCardiovascular Medicine Analytics Center, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.
Spyridon KostantinisDepartment of Internal Medicine, Yale School of Medicine, 330 Cedar Street, P.O. Box 208056, New Haven, CT 06510, USA.
Margaret FurmanSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.
Attila FeherSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.
Monique HinchcliffSection of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale School of Medicine, 300 Cedar Street, TAC S-541, P.O. Box 208031, New Haven, CT 06520-8031, USA.
Natasha CigarroaDepartment of Internal Medicine, Yale School of Medicine, 330 Cedar Street, P.O. Box 208056, New Haven, CT 06510, USA.
Guangyu TongSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.
Steffne J KunnirickalValley Health System, 4 Valley Health Plaza, Paramus, NJ 07652, USA.
Natalija OdanovicSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.
Samit M ShahSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, P.O. Box 208017, New Haven, CT 06520-8017, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autoimmune diseases (AD) are associated with increased cardiovascular risk, but their relationship with coronary vasomotor dysfunction (CVDys) in patients with angina with nonobstructive coronary arteries (ANOCA) remains unclear. Methods: We retrospectively analyzed 242 adults with ANOCA who underwent invasive coronary function testing. Patients were categorized by AD status, with systemic and organ-specific AD also evaluated separately. CVDys endotypes, including coronary microvascular dysfunction (CMD), vasospastic angina (VSA), and endothelial dysfunction, were compared using adjusted risk ratios. Clinical outcomes were assessed with time-to-event analyses. Results: Of 242 patients (74.8% female), 91 (37.6%) had AD. CVDys was common in both patients with and without AD (81.3% vs 80.8%; Conclusions: Autoimmune disease was not associated with higher CVDys prevalence or adverse cardiovascular outcomes in patients with ANOCA undergoing invasive CFT. Invasive testing identified diverse CVDys endotypes among patients with AD, supporting the utility of comprehensive phenotyping in this population.

Indexed as

Angina with nonobstructive coronary arteriesAutoimmune diseaseCoronary microvascular dysfunctionCoronary vasomotor dysfunctionEndothelial dysfunctionVasospastic angina

Identifiers

PMID42774444
PMCPMC13594533

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.