SynthesisFrontiers in nutrition2026
Total ultra-processed food intake and selected food-group exposures in relation to non-alcoholic fatty liver disease: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Background: Ultra-processed food (UPF) consumption has been linked to cardiometabolic diseases, but the association with non-alcoholic fatty liver disease (NAFLD) remains unclear. Moreover, whether all UPFs confer similar risk is unknown. Objective: To systematically review and meta-analyze the association between total UPF intake (strictly defined by NOVA classification) and selected UPF-related food-group exposures [red/processed meat and sugar-sweetened beverages (SSBs)] and NAFLD risk in adults. Methods: We searched PubMed, Web of Science, and Cochrane Library up to March 31, 2026, for observational studies reporting adjusted effect estimates for total UPF intake or selected food-group exposures and NAFLD. Study quality was assessed using the Newcastle-Ottawa Scale (NOS) or AHRQ criteria. Random-effects models pooled odds ratios (ORs) comparing highest vs. lowest intake categories. Subgroup and sensitivity analyses explored heterogeneity. Results: Twenty-four studies were included in the systematic review. Of these, Conclusion: Total UPF intake is associated with a moderate increase in NAFLD risk. Red/processed meat and sugar-sweetened beverages show stronger associations, suggesting that dietary recommendations may prioritize these high-risk food groups, although blanket avoidance of all UPFs is not directly supported by the current data.
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Registered trials
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