Evidence map›Paper›PMID 42775825›Full record

ArticleExperimental physiology2026

Women with a history of gestational diabetes mellitus have preserved sensory nerve-mediated dilatation in the cutaneous microvasculature.

Grace S Maurer, Kelsey S Schwartz, Diana I Jalal, Anna E Stanhewicz

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Grace S MaurerDepartment of Health, Sport, and Human Physiology, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-6952-5097
Kelsey S SchwartzDepartment of Health, Sport, and Human Physiology, University of Iowa, Iowa City, Iowa, USA.
Diana I JalalCarver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Anna E StanhewiczDepartment of Health, Sport, and Human Physiology, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-3941-3879

Funding

University of Iowa Institute for Clinical and Translational ScienceUM1TR004403 · NCATS · UNIVERSITY OF IOWA · PI Marlan R Hansen, Patricia Winokur · 2023 to 2026
$16.1M
PROGRAM IN HEMOSTASIS AND THROMBOSIS FOR ACADEMICT32HL007344 · NHLBI · UNIVERSITY OF IOWA · PI Anil Kumar Chauhan, Steven R Lentz · 1985 to 2026
$6.5M
The role of oxidative stress in reduced microvascular function after gestational diabetesR01HL169201 · NHLBI · UNIVERSITY OF IOWA · PI ANNA STANHEWICZ · 2023 to 2026
$2.4M
Endothelin-1 signaling in microvascular responses to insulin and the role of physical activity and sedentary behavior in women with a history of gestational diabetes mellitusF31HL177925 · NHLBI · UNIVERSITY OF IOWA · PI Grace Susan Maurer · 2025 to 2026
$77k
National Instutes of Health NIH F31HL177925 (G.S.M.)National Instutes of Health NIH HL169201 (A.E.S.)National Instutes of Health NIH UM1TR004403 (UI ICTS)National Instutes of Health T32 HL007344 (K.S.S.)NCATS NIH HHS UM1 TR004403NHLBI NIH HHS F31 HL177925NHLBI NIH HHS R01 HL169201NHLBI NIH HHS T32 HL007344
6 · The paper itself

Abstract

Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)-dependent mechanisms, persists after GDM. However, it is unknown whether cutaneous sensory nerve-mediated dilatation is similarly reduced in these women. We hypothesised that women with a history of GDM would exhibit attenuated sensory nerve-mediated vasodilatation compared with HC women. One intradermal microdialysis fibre was placed in the ventral forearm of 30 HC and 22 GDM women for the local delivery of lactated Ringer's solution during a local heating protocol (42°C; 0.1°C s

Indexed as

gestational diabetesmicrovasculaturesensory nerve

Identifiers

PMID42775825
PMCPMC13599599

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.