In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Ankit SabharwalDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0000-0003-4355-0355 Md Roushan AliDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0000-0002-8894-2566 Kyler S MitraDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0009-0000-0258-5987 Jun MorisueMitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0009-0005-0219-1984 Jace KleinDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0009-0007-6732-2572 Rishav SarkarDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0009-0002-7152-2044 Kaila SavageDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
Lucy Rai ThulungDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0009-0000-6402-4739 Amanda ZumbrockDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.
Cassidy PetreeGenes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.ORCID 0000-0002-9379-2400 Santiago Restrepo CastilloDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0000-0001-7881-1813 Mireya MotaDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0000-0002-7105-516X Gaurav K VarshneyGenes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.ORCID 0000-0002-0429-1904 Eiko Nakamuru-OgisoMitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0009-0003-2223-5628 Stephen C EkkerDepartment of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Texas, USA.ORCID 0000-0003-0726-4212 Funding
Systematic Vertebrate Functional GenomicsR01GM063904 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI EKKER, STEPHEN CARL · 2001 to 2025
$10.7MModeling mtDNA Disease in vivoR24OD035577 · OD · UNIVERSITY OF TEXAS AT AUSTIN · PI Stephen Carl Ekker · 2024 to 2026
$1.9MDevelopment of scalable methods for rapid phenotyping and functional testing of variantsR24OD034438 · OD · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI Gaurav K Varshney · 2024 to 2026
$1.8MSystematic Vertebrate Functional GenomicsR56GM063904 · NIGMS · MAYO CLINIC ROCHESTER · PI EKKER, STEPHEN CARL · 2009 to 2010
$611kNIGMS NIH HHS R01 GM063904NIGMS NIH HHS R56 GM063904NIH HHS R24 OD034438NIH HHS R24 OD035577
6 · The paper itselfAbstract
Pathogenic variants in the 13 protein-coding genes of the mitochondrial genome underlie clinically and biochemically heterogeneous disorders. Most mtDNA-encoded genes lack defined loss-of-function (LOF) models
Indexed as
DdCBEMitochondriamitochondrial base editingmitochondrial DNAzebrafishZ-Terminator
Identifiers
PMID42779741
PMCPMC13596318
What Socratic holds
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