ArticlebioRxiv : the preprint server for biology2026
Physiological landmarks reveal the laminar organization of the primate hippocampus.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
The laminar anatomy of the hippocampal microcircuit is conserved across mammals, and its physiology has been characterized extensively in rodents, yet how this circuitry is organized physiologically in the primate brain remains poorly understood. Here we used high-density Neuropixels probes to record simultaneously across the subfields of CA1, CA3 and the dentate gyrus in two awake macaques. Sharp-wave ripples and dentate spikes produced current source density signatures that provided physiological landmarks for CA1 and the dentate gyrus, enabling alignment of recordings to hippocampal cytoarchitecture. Theta-band (3-7 Hz) oscillatory activity occurred in discrete bouts whose prevalence peaked in the
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