Evidence map›Paper›PMID 42781255›Full record

ReviewWorld journal of gastrointestinal pathophysiology2026

Intersections of gastrointestinal dysbiosis of the gut microbiome and aging.

Sara Shu, Benjamin K P Woo

Abstract readReview
In one paragraph

Review in World journal of gastrointestinal pathophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sara ShuDepartment of Family Medicine, Mayo Clinic, Rochester, MN 55905, United States.
Benjamin K P WooChinese American Health Promotion Laboratory, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles Medical Center, Sylmar, CA 91104, United States. bkpwoo@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Geriatric syndromes such as frailty and sarcopenia are multidomain indicators of functional status in relation to the chronic disease burden of an aging adult. The human microbiota has gained increasing spotlight in regulating key aspects inherent of aging. In this review, we survey the current literature exploring the pathophysiological intersections of the gut microbiome and the aging process and associated geriatric syndromes that ultimately influence health span and lifespan. We discuss how intrinsic and extrinsic factors can influence age-related gut dysbiosis and propose areas of future directions for further research for identifying therapeutic targets to promote healthy aging.

Indexed as

AgingFrailtyGeriatricsGut microbiomeSarcopenia

Identifiers

PMID42781255
PMCPMC13598448

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.