Evidence map›Paper›PMID 42783591›Full record

ArticleJournal of market access & health policy2026

A Model-Based Public-Payer Investment Appraisal of a National Home Hemodialysis Program in Greece: A Net Present Value Analysis.

Vasileios Zavvos, John Fanourgiakis, Michael A Talias, Christos Iatrou, Christos Ntais

Abstract read
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Article in Journal of market access & health policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Vasileios ZavvosHealthcare Management Program, School of Social Sciences, Hellenic Open University, 26335 Patras, Greece.
John FanourgiakisDepartment of Management Science and Technology, Hellenic Mediterranean University, 72100 Agios Nikolaos, Greece.ORCID 0000-0001-5364-7412
Michael A TaliasHealthcare Management Program, School of Economics & Management, Open University of Cyprus, Nicosia 2220, Cyprus.ORCID 0000-0002-1802-5586
Christos IatrouCentre for Nephrology and Dialysis Unit, HYGEIA Hospital, 15123 Athens, Greece.
Christos NtaisHealthcare Management Program, School of Economics & Management, Open University of Cyprus, Nicosia 2220, Cyprus.ORCID 0000-0002-2749-101X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn-center hemodialysis is the dominant kidney replacement therapy modality in Greece and generates substantial recurring expenditure for the public payer. Home hemodialysis is not currently implemented at national scale, but it may reduce long-term public expenditure if early investment in training capacity, equipment and home support is recovered over time.

objectiveTo evaluate, from the Greek public-payer perspective, the discounted budget impact and net present value (NPV) of implementing a national home hemodialysis program for 300 patients.

methodsWe developed a deterministic investment-appraisal model comparing gradual implementation of home hemodialysis with continued in-center hemodialysis for the same projected cohort over 10 years. The in-center comparator was informed by a 2022 Greek patient-level micro-costing study. Home hemodialysis expenditure was constructed from explicit patient-flow equations, resource quantities, unit costs, capital purchases and hospital-tariff offsets. Annual incremental savings were discounted at 3% in the base case. Alternative discount rates, deterministic one-way sensitivity analyses and program-scale scenarios were examined. Fiscal benefit-cost ratio (BCR) and return on investment (ROI) were also calculated.

resultsUndiscounted 10-year public expenditure was EUR 69,681,804 for home hemodialysis and EUR 86,700,267 for continued in-center hemodialysis, yielding savings of EUR 17,018,463. During the first 5 years, the program required EUR 1,724,012 in additional expenditure. At a 3% discount rate, NPV was EUR 12,696,564, the fiscal BCR was 2.89, fiscal ROI was 189.3% and discounted payback occurred during year 6. NPV remained positive at 5% (EUR 10,391,382) and across all tested one-way scenarios (range EUR 706,179 to EUR 24,686,948).

conclusionsThe modeled national home hemodialysis program generated a positive 10-year public-payer NPV under the base-case and tested sensitivity assumptions. A positive NPV is not, however, a formal Greek health-system decision rule and does not capture health outcomes, patient and family costs, or equity. The findings support staged pilot implementation and prospective collection of Greek real-world data before wider rollout.

Indexed as

budget impactdialysis costsGreecehome hemodialysiskidney replacement therapynet present valuepublic payer

Identifiers

PMID42783591
PMCPMC13608129

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.