ArticleMarine drugs2026
Comparative Metabolomics Identifies Diterpene-Rich Marine Macroalgae with Potent Antiproliferative Activity Against Colorectal Cancer Cells.
Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Marine macroalgae constitutes an important source of structurally diverse secondary metabolites with significant pharmaceutical potential. In the present study, an untargeted liquid chromatography-mass spectrometry (LC-MS)-based metabolomic approach was integrated with biological screening to investigate the relationship between metabolite composition and antiproliferative activity in eight Mediterranean macroalgal species. Crude organic extracts were evaluated against the human colorectal cancer cell lines HT-29 and HCT-116, while the most active extracts were further investigated by flow cytometry to explore their cellular effects. Comparative metabolomic analysis revealed marked interspecific differences, with the brown algae
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