Evidence map›Paper›PMID 42784208›Full record

ArticleProteomes2026

A Circulating Proteomic Signature of Allostatic Load Is Associated with Multisystem Disease and Mortality.

Yufan Guan, Jie Shen, Li Li, Kai Zhang, Song Liu, Qianqian Zhu, Philip I Chow, Hongmei Jiang, Jing Li, Lifang Hou and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proteomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Yufan GuanDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Jie ShenDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Li LiDepartment of Family Medicine, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.ORCID 0000-0003-1802-9517
Kai ZhangDepartments of Public Health, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA.
Song LiuDepartment of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Qianqian ZhuDepartment of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.ORCID 0000-0003-2516-6675
Philip I ChowDepartment of Psychiatry and Neurobehavioral Sciences, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Hongmei JiangDepartment of Statistics and Data Science, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-2286-2544
Jing LiDivision of General Internal Medicine & Population Science, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Lifang HouDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Hua ZhaoDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.

Funding

CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - COORDINATING CENTER (CC)75N92023D00002 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, JING · 2023 to 2025
$6.8M
Homologous recombination repair capacity in peripheral blood lymphocytes as a breast cancer risk factorU01CA260731 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI LIU, SONG, ZHAO, HUA · 2022 to 2025
$2.5M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - OAKLAND FIELD CENTER75N92023D00003 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI BHATT, ANKEET S. · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - BIRMINGHAM FIELD CENTER75N92023D00005 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - CHICAGO FIELD CENTERDIVERSITY SUPPLEMENT FOR MORGANN WEST75N92023D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI CARNETHON, MERCEDES · 2023 to 2025
$2.1M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - UNIVERSITY OF MINNESOTA FIELD CENTER.75N92023D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI SCHREINER, PAMELA J · 2023 to 2025
$1.7M
Racial/ethnic disparity in breast cancer: can metabolic profiles play a role?U01CA179655 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ZHAO, HUA · 2013 to 2017
$1.7M
Mitochondrial dysfunction and chronic stress intersect as mechanisms driving breast cancer racial disparitiesR21CA267975 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI SHOCK, LISA SALE, ZHAO, HUA · 2022 to 2023
$396k
NCI NIH HHS R21 CA267975NCI NIH HHS R21CA267975NCI NIH HHS U01 CA179655NCI NIH HHS U01CA179655NCI NIH HHS U01 CA260731NCI NIH HHS U01CA260731NHLBI NIH HHS 75N92023D00002NHLBI NIH HHS 75N92023D00003NHLBI NIH HHS 75N92023D00004NHLBI NIH HHS 75N92023D00005NHLBI NIH HHS 75N92023D00006
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

allostatic loadchronic diseasesmorbiditymortalityproteomes

Identifiers

PMID42784208
PMCPMC13611500

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.