Evidence map›Paper›PMID 42786687›Full record

ArticleExperimental physiology2026

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats.

Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J Michael, Vincent Joseph, Richard Kinkead

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marianne GagnonResearch Center of the Quebec Heart and Lung Institute, Quebec City, Quebec, Canada.ORCID https://orcid.org/0000-0001-7799-5112
Stéphanie FournierResearch Center of the Quebec Heart and Lung Institute, Quebec City, Quebec, Canada.ORCID https://orcid.org/0000-0002-7018-3047
François MarcouillerResearch Center of the Quebec Heart and Lung Institute, Quebec City, Quebec, Canada.
Natalie J MichaelResearch Center of the Quebec Heart and Lung Institute, Quebec City, Quebec, Canada.
Vincent JosephResearch Center of the Quebec Heart and Lung Institute, Quebec City, Quebec, Canada.ORCID https://orcid.org/0000-0003-3571-9042
Richard KinkeadResearch Center of the Quebec Heart and Lung Institute, Quebec City, Quebec, Canada.ORCID https://orcid.org/0000-0001-9686-2577

Funding

CIHR PJT-162232CIHR PJT-173396
6 · The paper itself

Abstract

Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences. While SA is typically more common in men, its prevalence in women increases sharply after menopause, implicating the loss of ovarian hormones in its pathogenesis. Despite the potential of hormone replacement therapy to modulate SA, the physiological mechanisms linking loss of ovarian function to SA remain unclear. Using an integrative approach, we investigated the combined effects of surgical removal of the ovaries (ovariectomy; OVX) and a 7-day moderate intermittent hypoxia protocol (IH; 30s at

Indexed as

HPA axisintermittent hypoxialeptinmenopauseovarian hormonesrespiratory controlsex‐based differencessleep apnoea

Identifiers

PMID42786687
PMCPMC13612877

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.