ArticleFrontiers in public health2026
Economic burden of hospital-acquired multidrug-resistant organism infections in patients undergoing gastrointestinal surgery: a bootstrap-based retrospective cohort study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Multidrug-resistant organism (MDRO) infections impose substantial clinical and economic burdens on surgical patients. However, specialty-specific analyses remain limited. This study quantified the economic impact of MDRO hospital-acquired infections (HAIs) on patients undergoing gastrointestinal surgery. Methods: 100 patients with postoperative HAIs at a tertiary hospital (January 2022-December 2024) were stratified into MDRO ( Results: The MDRO had significantly longer ICU stay (median 2 vs. 0 days; Conclusion: The study demonstrate that HAIs caused by MDROs in gastrointestinal surgery patients exacerbate medical resource consumption and significantly increase hospitalization costs, prolonging hospital stay duration, ICU length of stay, and duration of antibiotic therapy. Consequently, these infections impose a significant economic burden, with laboratory diagnostics, non-surgical treatments and clinical diagnostic procedures identified as the major cost drivers. We fully acknowledge that, as a retrospective observational study, comparing the MDRO and non-MDRO groups cannot establish that MDRO infection caused the increased costs, without adequate adjustment for confounding factors (e.g., severity of underlying illness, age, length of hospital stay prior to ICU admission).
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