Evidence map›Paper›PMID 42787728›Full record

ReviewFrontiers in immunology2026

Targeting the Th17/Treg axis: from immunological insights to therapeutic avenues in atherosclerosis.

Zhang Qin, Siqing Chen, Zhe Lyu, Fengyun Zhou, Le Liu, Qi Ai, Zhuo Zeng

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhang Qin *The Fourth Hospital of Changsha (Changsha Hospital of Hunan Normal University), Changsha, Hunan, China.
Siqing Chen *The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Zhe LyuThe Fourth Hospital of Changsha (Changsha Hospital of Hunan Normal University), Changsha, Hunan, China.
Fengyun ZhouThe Fourth Hospital of Changsha (Changsha Hospital of Hunan Normal University), Changsha, Hunan, China.
Le LiuThe Fourth Hospital of Changsha (Changsha Hospital of Hunan Normal University), Changsha, Hunan, China.
Qi AiThe Fourth Hospital of Changsha (Changsha Hospital of Hunan Normal University), Changsha, Hunan, China.
Zhuo ZengThe Fourth Hospital of Changsha (Changsha Hospital of Hunan Normal University), Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paradigm of atherosclerosis has evolved from a passive lipid storage disease to a dynamic immuno-inflammatory disorder, yet the precise immune checkpoints governing its progression remain a therapeutic frontier. This review dissects the yin-yang regulation exerted by CD4

Indexed as

AtherosclerosisTh17 CellsT-Lymphocytes, RegulatoryAnimalsHumansImmunotherapyatherosclerosischronic vascular inflammationTh17therapiesTreg

Identifiers

PMID42787728
PMCPMC13603021

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.