Evidence map›Paper›PMID 42789403›Full record

ArticleDrug delivery2026

Numerical simulation of PDRN iontophoresis: comparison with passive diffusion and key parameter analysis.

Jongho Cho, Dongjun Han, Hyemi Lee, Dong-Wook Park

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jongho ChoSchool of Electrical and Computer Engineering, University of Seoul, Seoul, Republic of Korea.
Dongjun HanSchool of Electrical and Computer Engineering, University of Seoul, Seoul, Republic of Korea.
Hyemi LeeDepartment of BioHealth and Eco-Up Convergence, University of Seoul, Seoul, Republic of Korea.
Dong-Wook ParkSchool of Electrical and Computer Engineering, University of Seoul, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polydeoxyribonucleotide (PDRN) is a bio-derived therapeutic agent known to exhibit regenerative, angiogenic, and anti-inflammatory effects. However, its relatively large molecular size limits penetration across the skin barrier, thereby reducing the feasibility of noninvasive transdermal delivery. Iontophoresis is a promising approach for enhancing the transport of charged macromolecules, yet quantitative understanding of PDRN iontophoresis remains limited. Here, we present an

Indexed as

IontophoresisPolydeoxyribonucleotidesAdministration, CutaneousAnimalsComputer SimulationDiffusionDrug Delivery SystemsHumansModels, BiologicalPermeabilitySkinSkin AbsorptionPolydeoxyribonucleotidesIontophoresisNernst–Planck equationnumerical simulationpolydeoxyribonucleotide (PDRN)transdermal drug delivery

Identifiers

PMID42789403
PMCPMC13618095

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.