ArticleAntioxidants (Basel, Switzerland)2026
Viridicatin from the Antarctic Fungus
Cristian Paz, Muhammad Javid Iqbal, Andrea Cristina Paula Lima, Alejandro Luarte, Pablo Lazcano, Ursula Wyneken, María Isabel Behrens, Daniela Ponce, Nicole Jeraldo, Sigisfredo Garnica and 6 more
Abstract read
In one paragraphArticle in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Cristian PazLaboratory of Natural Products & Drug Discovery, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco 4780000, Chile.ORCID 0000-0002-4668-4984 Muhammad Javid IqbalLaboratory of Natural Products & Drug Discovery, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco 4780000, Chile.ORCID 0009-0004-2913-1765 Andrea Cristina Paula LimaBiomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.ORCID 0000-0002-0466-7561 Pablo LazcanoIMPACT-Center of Interventional Medicine for Precision and Advanced Cellular Therapy, Santiago 7620001, Chile.ORCID 0000-0001-9218-5396 María Isabel BehrensCenter for Advanced Clinical Research (CICA), Clinical Hospital of the University of Chile, Santiago 8380447, Chile.ORCID 0000-0003-0964-426X Daniela PonceCenter for Advanced Clinical Research (CICA), Clinical Hospital of the University of Chile, Santiago 8380447, Chile.
Nicole JeraldoCenter for Advanced Clinical Research (CICA), Clinical Hospital of the University of Chile, Santiago 8380447, Chile.
Sigisfredo GarnicaLaboratorio de Micología, Instituto de Bioquímica y Microbiología, Universidad Austral de Chile, Valdivia 5090000, Chile.
Cecilia VillegasDepartamento de Ciencias Biológicas y Químicas, Facultad de Recursos Naturales, Universidad Católica de Temuco, Temuco 4780000, Chile.ORCID 0000-0002-9066-1763 Vaderament-A Nchiozem-NgnitedemInstitut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0001-8337-9260 Bernd SchmidtInstitut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0002-0224-6069 Eric SperlichInstitut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.ORCID 0000-0002-3118-9518 Nicole CortezLaboratory of Natural Products & Drug Discovery, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco 4780000, Chile.
Viviana BurgosEscuela de Tecnología Médica, Facultad de Salud, Universidad Santo Tomás, Temuco 4780000, Chile.
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Neurodegenerative diseases remain a major therapeutic challenge, with oxidative stress playing a central role in central and peripheral immune system dysfunction that leads to neuronal loss. Natural products from extreme environments represent an underexplored source of neuroprotective agents. In this study, viridicatin, a quinoline-derived alkaloid, was isolated from the Antarctic fungus
Indexed as
Antarctic funguscell protectionin silicomicrogliaNrf2/KEAP1 pathwayoxidative stressviridicatin
Identifiers
PMID42792128
PMCPMC13603828
What Socratic holds
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