Evidence map›Paper›PMID 42793210›Full record

ArticleCurrent issues in molecular biology2026

Preclinical In Vitro Evaluation of an Innovative Nutraceutical Mixture Modulating the Histamine H1 Receptor-Preliminary Data.

Franco Frati, Carlo Cavaliere, Francesco Frati, Giulio Torello, Marianna Colasante, Chiara Caputo, Marta Scquizzato, Simonetta Masieri

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Franco FratiPrivate Independent Researcher, 20123 Milano, Italy.
Carlo CavaliereDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-0378-8935
Francesco FratiClinic of Otolaryngology (ENT), University of Perugia, 06123 Perugia, Italy.
Giulio TorelloTL Pharma Consulting, 65129 Pescara, Italy.ORCID 0009-0007-7289-513X
Marianna ColasanteTL Pharma Consulting, 65129 Pescara, Italy.
Chiara CaputoScience Department Global Pharmacies Partner, 20123 Milano, Italy.
Marta ScquizzatoScience Department Global Pharmacies Partner, 20123 Milano, Italy.
Simonetta MasieriDepartment of Oral and Maxillofacial Sciences, Sapienza University, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary pathogenic mechanism of Type I hypersensitivity reactions involves histamine-mediated activation of the H1 receptor (H1R) and the subsequent signaling of the phospholipase C β-inositol trisphosphate (PLCβ-IP

Indexed as

allergydrugsH1 receptorhistamineNutraceuticals

Identifiers

PMID42793210
PMCPMC13605393

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.