Evidence map›Paper›PMID 42794468›Full record

ArticleInternational journal of molecular sciences2026

Targeted 3.34-Million CpG Site Sequencing Reveals Preliminary Cord Blood Epigenetic Alterations of Autism Spectrum Disorder: A Pilot Study Highlighting the

Marina Armas-González, Nieves Luisa González-González, Enrique González-Dávila, Olivia Orribo-Morales, José Ramón Castro-Conde, Candelaria González-Campos, Carlos Flores, José Miguel Lorenzo-Salazar, Rafaela González-Montelongo, Adrián Muñoz-Barrera and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marina Armas-GonzálezObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.
Nieves Luisa González-GonzálezObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.ORCID 0000-0003-1401-5580
Enrique González-DávilaMathematics, Statistics and Operations Research Department (IMAULL), University of La Laguna (ULL), 38320 La Laguna, Spain.ORCID 0000-0002-0781-9161
Olivia Orribo-MoralesObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.
José Ramón Castro-CondeObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.ORCID 0000-0003-0867-2920
Candelaria González-CamposObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.
Carlos FloresResearch Unit, Hospital Universitario Ntra. Sra. de Candelaria, Instituto de Investigación Sanitaria de Canarias (IISC), 38010 Santa Cruz de Tenerife, Spain.ORCID 0000-0001-5352-069X
José Miguel Lorenzo-SalazarGenomics Division, Instituto Tecnológico y de Energías Renovables (ITER), 38600 Santa Cruz de Tenerife, Spain.ORCID 0000-0002-5135-2861
Rafaela González-MontelongoGenomics Division, Instituto Tecnológico y de Energías Renovables (ITER), 38600 Santa Cruz de Tenerife, Spain.ORCID 0000-0001-9022-8663
Adrián Muñoz-BarreraGenomics Division, Instituto Tecnológico y de Energías Renovables (ITER), 38600 Santa Cruz de Tenerife, Spain.ORCID 0000-0002-1561-5898
Erika Padrón-PérezObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.ORCID 0000-0001-5243-3244
Laura Tascón-PadrónDepartment of Obstetrics and Prenatal Medicine, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-9941-9001
María Núñez CatalánObstetrics and Gynecology Department, Sección de Medicina, Facultad de Ciencias de la Salud, University of La Laguna (ULL), 38320 La Laguna, Spain.

Funding

Instituto de Salud Carlos III PI18/01700
6 · The paper itself

Abstract

Rising reported Autism Spectrum Disorder (ASD) prevalence underscores the need to explore early perinatal biological markers. To conduct an exploratory pilot investigation of cord blood DNA methylation patterns as potential early epigenetic candidate loci associated with ASD in infants born to mothers with obesity and gestational diabetes. This prospective pilot study analyzed 14 mother-infant pairs comprising infants born to mothers with obesity and gestational diabetes later diagnosed with ASD (

Indexed as

Autism Spectrum DisorderCadherinsCpG IslandsDNA MethylationEpigenesis, GeneticFetal BloodAdultCase-Control StudiesDiabetes, GestationalFemaleHumansInfantMalePilot ProjectsPregnancyProspective StudiesCadherinsautismcord blooddiabetesDNAenrichment analysisepigeneticmaternal obesityneurodevelopmentpregnancyprotocadherins

Identifiers

PMID42794468
PMCPMC13607789

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.