Evidence map›Paper›PMID 42794901›Full record

ReviewCancers2026

Delayed Lymphatic Reconstruction for Breast Cancer-Related Lymphedema.

Judith Monzy, Jocelyn Lu, Ara A Salibian, Philip S Brazio, Ketan M Patel

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Judith MonzyDivision of Plastic and Reconstructive Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0003-0497-7866
Jocelyn LuDivision of Plastic and Reconstructive Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Ara A SalibianDivision of Plastic and Reconstructive Surgery, Department of Surgery, UC Davis Medical Center, Sacramento, CA 95817, USA.
Philip S BrazioDivision of Plastic and Reconstructive Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Ketan M PatelDivision of Plastic and Reconstructive Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer-related lymphedema (BCRL) is a chronic disease that stems from damage to the lymphatic system due to breast cancer treatment leading to interstitial fluid buildup in the affected extremity. Patients with axillary lymph node dissection in combination with radiation therapy are at the highest risk of developing lymphedema. The mainstay non-surgical treatment involves participation in complete decongestive therapy with certified lymphedema therapists, daily compression garment usage, at-home pump treatments, and diligent skin care. Surgical treatments options can help alleviate symptoms associated with the disease by improving lymphatic drainage and removing fibrofatty tissue. Immediate lymphatic reconstruction (ILR) involves reconstructing cut lymphatics prophylactically at the time of axillary dissection with lymphovenous bypass (LVB) to decrease the risk of developing lymphedema. Delayed reconstruction addresses clinically diagnosed lymphedema and is divided into physiologic and debulking surgical techniques. Physiologic surgeries include lymphovenous bypass and vascularized lymph node transplantation (VLNT) aimed to treat fluid buildup. Debulking surgeries include lymphatic sparing liposuction or direct excision of fibrofatty tissues in the affected extremity to treat excess fibrofatty tissue secondary to lymphedema. This review discusses the pathophysiology of BCRL, diagnosis and staging of the disease, as well as provides an algorithmic overview on delayed lymphatic reconstruction options for BCRL.

Indexed as

breast cancer-related lymphedemaimmediate lymphatic reconstructionliposuctionlymphovenous bypassvascularized lymph node transfer

Identifiers

PMID42794901
PMCPMC13604093

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.