Evidence map›Paper›PMID 42795513›Full record

ReviewMicroorganisms2026

Vaginal Ecosystem During Gestation and Puerperium: Microbiota, Dysbiosis, Infection and Fetal-Maternal Implications.

Antonio Braga, Gustavo Ribeiro Lima, Fernanda da Costa Negraes, Maria Vitória Moura Fajardo, Karine Mello Duvivier, Luis Fernando Lima Bueno, Susana Cristina Aidé Viviani Fialho, Edward Araujo Júnior, Jorge Rezende-Filho

Abstract readReview
PubMed Publisher
In one paragraph

Review in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio BragaDepartment of Gynecology and Obstetrics, School of Medicine, Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro 22240-003, RJ, Brazil.ORCID 0000-0002-2942-6182
Gustavo Ribeiro LimaService of Gynecology and Obstetrics, Antônio Pedro University Hospital, Fluminense Federal University, Niterói 24070-090, RJ, Brazil.ORCID 0000-0001-6106-6503
Fernanda da Costa NegraesService of Gynecology and Obstetrics, Antônio Pedro University Hospital, Fluminense Federal University, Niterói 24070-090, RJ, Brazil.ORCID 0000-0002-1068-9580
Maria Vitória Moura FajardoService of Gynecology and Obstetrics, Antônio Pedro University Hospital, Fluminense Federal University, Niterói 24070-090, RJ, Brazil.
Karine Mello DuvivierService of Gynecology and Obstetrics, Antônio Pedro University Hospital, Fluminense Federal University, Niterói 24070-090, RJ, Brazil.ORCID 0009-0001-3192-8499
Luis Fernando Lima BuenoDiscipline of Gynecology and Obstetrics, Santo Amaro University (UNISA), São Paulo 04829-300, SP, Brazil.ORCID 0009-0005-1831-5638
Susana Cristina Aidé Viviani FialhoService of Gynecology and Obstetrics, Antônio Pedro University Hospital, Fluminense Federal University, Niterói 24070-090, RJ, Brazil.ORCID 0000-0002-4212-0022
Edward Araujo JúniorDepartment of Obstetrics, Paulista School of Medicine, Federal University of São Paulo, São Paulo 04023-062, SP, Brazil.ORCID 0000-0002-6145-2532
Jorge Rezende-FilhoDepartment of Gynecology and Obstetrics, School of Medicine, Maternity School, Federal University of Rio de Janeiro, Rio de Janeiro 22240-003, RJ, Brazil.ORCID 0000-0002-2193-3374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vaginal ecosystem undergoes profound physiological adaptations during pregnancy and the puerperium through dynamic interactions among the vaginal microbiota, epithelial barrier, local immune system, and hormonal milieu. Disruption of this homeostasis may lead to vaginal dysbiosis and infection, with potential consequences for maternal, fetal, and neonatal health. This narrative review aimed to provide a comprehensive and updated overview of the vaginal ecosystem throughout pregnancy and the puerperium, integrating current evidence on physiological changes in the vaginal microbiota, mechanisms of dysbiosis, major vaginal infections, diagnostic approaches, therapeutic management, and maternal-fetal implications. A structured literature search was conducted in PubMed/MEDLINE and Scopus through July 2026. Priority was given to recent systematic reviews, meta-analyses, international clinical guidelines, randomized clinical trials, and observational studies addressing the vaginal microbiota, dysbiosis, bacterial vaginosis, vulvovaginal candidiasis, trichomoniasis, aerobic vaginitis, pregnancy, and the puerperium. Pregnancy is generally characterized by a stable, low-diversity,

Indexed as

aerobic vaginitisbacterial vaginosisprecision medicinepregnancyvaginal dysbiosisvaginal microbiome

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.