Evidence map›Paper›PMID 42797001›Full record

ReviewNutrients2026

Anthocyanin-Induced Alterations in Substrate Oxidation During Exercise: A Narrative Review.

Matthew D Cook, James L Bateman, Mark E T Willems

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthew D CookSchool of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester WR2 6AJ, UK.ORCID 0000-0002-6293-7566
James L BatemanSchool of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester WR2 6AJ, UK.
Mark E T WillemsSchool of Sport, Science and Engineering, University of Chichester, College Lane, Chichester PO19 6PE, UK.ORCID 0000-0003-4385-8739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bioactive flavonoid compound anthocyanin that is present in berries and other pigmented fruits has received interest for effects on substrate oxidation during exercise. The databases MEDLINE (via PubMed) and SPORTDiscus (via EBSCOhost) were searched from 4 March to 5 August 2026 for trials examining the exercise-induced metabolic effects of anthocyanin-rich foods and supplements. Twenty-three studies were included in this narrative review with observations from blackcurrant, blueberry, tart cherry, blackberry and elderberry. After short-term supplementation (up to 14 days), extract from New Zealand grown blackcurrants provided the strongest evidence, with many studies reporting up to 30% increases in fat oxidation and typically ~5-12% decreases in carbohydrate oxidation during continuous moderate-intensity exercise (cycling, walking and running). The exercise-induced metabolic responses appear to be influenced by the baseline respiratory exchange ratio, body composition, duration of dosing, and environmental exercise conditions. The findings for effects from other anthocyanin-rich sources were few and less clear. New Zealand blackcurrant extract increases moderate-intensity exercise-induced fat oxidation without alteration of the total energy expenditure. Mechanistic evidence for blackcurrant-induced effects suggests altered intramuscular triglyceride use and glycogen availability. Information from other anthocyanin-rich sources is limited for now. It cannot be excluded, however, that the changes in exercise-induced substrate oxidation may be anthocyanin-type (and thus berry) dependent, but more studies are needed on other anthocyanin-rich non-blackcurrant sources. Future studies are required to confirm mechanisms. And studies with experimental design and methodology are needed to examine responsiveness and the factors that may play a role, such as training status, exercise modality, age, and habitual diet, to advance our understanding for the implications of anthocyanin-rich supplementation for sport and exercise nutrition.

Indexed as

AnthocyaninsExerciseCarbohydrate MetabolismDietary SupplementsEnergy MetabolismFruitGlycogenHumansLipid MetabolismOxidation-ReductionPlant ExtractsRibesAnthocyaninsGlycogenPlant Extractsanthocyaninscarbohydrate metabolismexerciselipid metabolismpolyphenols

Identifiers

PMID42797001
PMCPMC13610498

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.