In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors.
Paul J SapienzaDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.ORCID 0000-0001-5279-3653 Trevor R MileurDepartment of Biochemistry and Biophysics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-4538-9764 Muhammad S KhanDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.
Kelin LiDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.ORCID 0000-0002-8630-2928 Jeffrey AubéDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.ORCID 0000-0003-1049-5767 Andrew L LeeDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.ORCID 0000-0003-2783-1907 Funding
Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JAMES E BEAR · 1985 to 2026
$201.5MTRD3 NMRbox: Bayesian AnalyticsP41GM111135 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HOCH, JEFFREY C · 2015 to 2024
$14.0MMechanisms and dynamics of allosteric function in proteinsR35GM144348 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Andrew L Lee · 2022 to 2026
$2.6MStructural and Dynamic Mechanisms in Classical Protein AllosteryR01GM127698 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEE, ANDREW L · 2019 to 2021
$1.2MNCI NIH HHS P30 CA016086NIGMS NIH HHS P41 GM111135NIGMS NIH HHS R01 GM127698NIGMS NIH HHS R35 GM144348
6 · The paper itselfAbstract
Positive cooperativity in ligand binding is a hallmark of allosteric oligomers, yet how the first binding event enhances the second remains obscure, because the pivotal singly-bound intermediate (lig
Indexed as
AllosteryBiological SciencesBiophysics and Computational BiologyEntropyNMRProtein Dynamics
Identifiers
PMID42798384
PMCPMC13605726
What Socratic holds
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