Evidence map›Paper›PMID 42798805›Full record

ReviewFrontiers in molecular biosciences2026

Functions and mechanisms of miR-650 in human diseases.

Qingmiao Shi, Chengran Gao, Chen Xue

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qingmiao ShiThe First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, China.
Chengran GaoThe First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chen XueThe First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are endogenous, single-stranded, small non-coding RNAs that play central roles in gene expression regulation. Among them, miR-650 has received increasing attention over the past decade because it regulates cell proliferation, differentiation, apoptosis, metabolism, cell cycle control, immune responses, and development. miR-650 has been studied in both neoplastic and non-neoplastic disease contexts. This review summarizes the expression characteristics of miR-650 in human diseases and discusses its roles in disease initiation and progression, the pathways in which it participates, and the upstream and downstream regulatory mechanisms involved. We also discuss the potential clinical value of miR-650 in disease diagnosis and therapy. Defining shared pathways across diseases and disease-subtype-specific expression patterns within miR-650-related regulatory networks may help identify more precise therapeutic targets.

Indexed as

cancerceRNAfunctionmechanismmiR-650non-neoplastic disease

Identifiers

PMID42798805
PMCPMC13613049

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.