ArticleACS omega2026
Process Simulation of Isoprene Recovery from Dilute Fermentation Off-Gas Using Absorption-Desorption.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
2 authors.
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Abstract
The recovery of biobased isoprene from dilute fermentation off-gas remains a major challenge due to low product concentrations and energy-intensive downstream separations. In this study, a process intensification strategy based on absorption-desorption was developed and evaluated to efficiently recover isoprene from air mixtures. The proposed system integrates absorption using 3-methyltridecane, vacuum degassing, steam stripping, and condensation with multiple recycle loops for solvent, water, and residual isoprene. Of the thermodynamic models examined, the Peng-Robinson equation of state was used for the absorption section while UNIFAC was used for steam stripping. Process optimization demonstrated up to 95% isoprene recovery and 98% product purity while significantly reducing energy consumption. Sensitivity analyses revealed that solvent temperature, solvent-to-feed ratio, and feed isoprene concentration strongly influence process efficiency, with energy demand decreasing from 26 to 10 MJ kg
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Registered trials
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