ArticlePediatric research2026
Impact of a multidisciplinary intervention on resting and exercise respiratory functions in adolescents with obesity.
Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
13 authors.
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Abstract
backgroundRespiratory function (RF), body composition (BC), and cardiorespiratory fitness (CRF) links remain underexplored during multidisciplinary weight loss interventions (MWLI) in adolescents with obesity.
objectivesTo investigate the impact of a 16-week MWLI on resting and exercise RFs and their associations with BC and CRF.
methodsRFs were measured in 92 adolescents (13.1 ± 1.19 years, 58%female, BMI 34.31 ± 4.93 kg/m²) by spirometry and at several intensities during cardiopulmonary exercise tests (CPET) before MWLI (T0) and after (T1). BC and CRF were measured by dual X-ray absorptiometry and peak oxygen consumption (VO
resultsBetween T0 and T1, forced vital capacity (FVC), expiratory volume in one second (FEV1) and median expiratory flow (MEF25-75) increased (p < 0.001). Ventilatory efficiency increased (p < 0.01), while VO
conclusionMWLI improves respiratory health and exercise tolerance in association with BC and CRF. IMPACT: This study is among the first to examine the effects of a multidisciplinary weight-loss intervention on both resting and exercise respiratory function in adolescents with obesity. The intervention improved respiratory function, body composition, and cardiorespiratory fitness. Respiratory improvements were associated with decreases in total, trunk, and visceral fat mass percentages and increases in lean mass percentage and cardiorespiratory fitness. The observed improvements in ventilatory efficiency and breathing reserve suggest a lower work of breathing and fewer ventilatory limitations during exercise, supporting multidisciplinary lifestyle interventions to improve respiratory health and exercise tolerance.
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Registered trials
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