Evidence map›Paper›PMID 42801089›Full record

ArticleJournal of inflammation research2026

Hotspots and Emerging Trends in JAK Inhibitor Therapy for Vitiligo: A Bibliometric Analysis (2015-2025).

Yubin Peng, Jindi Feng, Lu Lu, Huimin He, Anqi Xie, Shiyu Zhang, Lu Yang, Yuehua Liu, Tao Wang

Abstract read
In one paragraph

Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yubin PengDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.ORCID 0009-0003-4375-7337
Jindi FengDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Lu LuDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Huimin HeDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Anqi XieDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Shiyu ZhangDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Lu YangDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Yuehua LiuDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.
Tao WangDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, People's Republic of China.ORCID 0000-0002-9998-2862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vitiligo is an acquired depigmented skin disease that severely impairs the patients' quality of life. In recent years, Janus kinase (JAK) inhibitors have become a research hotspot in vitiligo treatment. However, systematic trend analysis and visualization of research mapping in this field are lacking. This study seeks to characterize the evolution of JAK inhibitor therapy for vitiligo from 2015 to 2025. Methods: A search was conducted in the Web of Science focusing on JAK inhibitor therapy for vitiligo from 2015 to 2025, including Article and Review Article in English, on March 1, 2026. VOSviewer, CiteSpace, Scimago Graphica, and Microsoft Excel 2021 were used for the bibliometric analysis and visualization. Meanwhile, the verification was conducted using the PubMed database. Results: A total of 268 publications appeared in this research area over the 2015-2025 period. Most of them originated from the United States and China. The most influential contributor was Harris John E. with the highest co-citation count. Conclusion: This article summarizes the current research landscape and emerging advances in JAK inhibitors therapy for vitiligo. JAK inhibitor research in vitiligo has undergone a paradigm shift from non-specific immunosuppression to targeted blockade of the IFN-γ-CXCL9/10 inflammatory axis, providing a valuable reference for future research in this field.

Indexed as

bibliometricsinflammatory signalingJAK inhibitorsJAK-STAT pathwayruxolitinibvitiligo

Identifiers

PMID42801089
PMCPMC13615764

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.