Evidence map›Paper›PMID 42801160›Full record

ReviewJournal of inflammation research2026

Nutrition and Endometriosis: Current Evidence on Dietary Risk Factors and Clinical Impact - A Narrative Review.

Christine Dawczynski, Jule Raschke, Lea Klein, Isabelle Schmidt, Svea Eichler, Marie Förster, Renata Voltolini Velho, Barbora Knappe-Drzikova, Sylvia Mechsner, Deborah Maier and 7 more

Abstract readReview
In one paragraph

Review in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Christine DawczynskiInstitute of Nutritional Sciences, Junior Research Group Nutritional Concepts, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-4063-6199
Jule RaschkeInstitute of Nutritional Sciences, Junior Research Group Nutritional Concepts, Friedrich Schiller University Jena, Jena, Germany.
Lea KleinInstitute of Nutritional Sciences, Junior Research Group Nutritional Concepts, Friedrich Schiller University Jena, Jena, Germany.
Isabelle SchmidtInstitute of Nutritional Sciences, Junior Research Group Nutritional Concepts, Friedrich Schiller University Jena, Jena, Germany.ORCID 0009-0003-8125-4941
Svea EichlerInstitute of Nutritional Sciences, Junior Research Group Nutritional Concepts, Friedrich Schiller University Jena, Jena, Germany.
Marie FörsterInstitute of Nutritional Sciences, Junior Research Group Nutritional Concepts, Friedrich Schiller University Jena, Jena, Germany.
Renata Voltolini VelhoCharité - Universitätsmedizin Berlin, Department of Gynecology Charité Center for Oncological Surgery, Endometriosis Research Centre Charité, Berlin, Germany.
Barbora Knappe-DrzikovaCharité - Universitätsmedizin Berlin, Department of Gynecology Charité Center for Oncological Surgery, Endometriosis Research Centre Charité, Berlin, Germany.
Sylvia MechsnerCharité - Universitätsmedizin Berlin, Department of Gynecology Charité Center for Oncological Surgery, Endometriosis Research Centre Charité, Berlin, Germany.
Deborah MaierImmundiagnostik AG, Bensheim, Germany.
Sven-Bastiaan HaangeDepartment of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.ORCID 0000-0003-2952-1152
Ulrike E Rolle-KampczykDepartment of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.ORCID 0000-0002-7728-6284
Martin Von BergenDepartment of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.
Madeleine HeldClinical and Biological Psychology, Ulm University, Ulm, Germany.ORCID 0009-0007-8148-157X
Suchithra VaradarajanClinical and Biological Psychology, Ulm University, Ulm, Germany.
Melissa HitzlerClinical and Biological Psychology, Ulm University, Ulm, Germany.ORCID 0000-0003-3119-5376
Iris KolassaClinical and Biological Psychology, Ulm University, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis (EM) is a severe chronic inflammatory disease characterized by the presence of endometrium-like tissue outside the uterine cavity, causing pain and significantly reducing quality of life. Worldwide, around 10% of women of reproductive age are affected and there is no cure as of now. The limited treatment options focus on hormone therapy, surgery and pain management--without satisfactory long-term effects. Nutritional strategies might support the prevention and treatment of EM-associated pain as nutrients and phytochemicals exert anti-inflammatory and antioxidant effects, modulate the immune system and hormonal balance. In addition, diet is a key determinant of the composition, health, and function of the gut microbiome. To identify the multitude of potential nutrition-related factors that influence the clinical picture of EM, we conducted a targeted literature search in PubMed, Web of Science, and Google Scholar in 2025. This narrative review examines the association of thirteen areas-including macro- and micronutrients, dietary patterns, contaminants, allergens, and food intolerances-with the risk of EM and therapeutic options. At present, there is only limited scientific evidence regarding the therapeutic benefits of dietary strategies. There are promising indications for the supportive potential of an anti-inflammatory diet, based on elements of the MedD resulting in a regular intake of long-chain n-3 polyunsaturated fatty acids, secondary plant compounds, dietary fibers, vitamins, minerals and trace elements. Certain foods (or food groups) may contribute to a worsening of symptoms in individual patients with EM (eg, cruciferous vegetables, foods containing histamine, gluten, FODMAPs). Since these foods usually provide important nutrients, avoiding them as a preventive measure can lead to nutrient deficiencies. Therefore, individual assessment is required to determine the extent to which these foods are tolerated by women diagnosed with EM. To clarify the supportive role of personalized nutritional concepts to support therapy of EM, there is an urgent need for further high-quality studies.

Indexed as

dietary fat and fatty acidsdietary protein and essential amino acidselimination dietsendometriosisfood additivesMediterranean dietmineralsprobioticssecondary plant compoundstrace elementsvitamins

Identifiers

PMID42801160
PMCPMC13615762

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.