ArticleWorld journal of microbiology & biotechnology2026
Genomic and metabolomic insights into carotenoid biosynthesis in a novel deep-sea bacterium, Paracoccus niotae sp. nov., isolated from an Arabian Sea seamount.
Article in World journal of microbiology & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural microbial carotenoids are increasingly recognized as alternatives to synthetic pigments because of their broad applications in the food, pharmaceutical, nutraceutical, cosmetic, feed, and aquaculture industries. In this study, a bright orange-pigmented deep-sea bacterium, strain NIOT.M2S5SZ12ᵀ, isolated from Arabian Sea seamount sediment, was comprehensively characterized to evaluate its carotenoid biosynthetic potential and taxonomic status. Phylogenetic analysis placed the strain within the genus Paracoccus, while whole-genome sequencing generated a 3.6 Mb draft genome with a GC content of 68.50 mol%. Genome-based taxonomic analyses yielded maximum digital DNA-DNA hybridization and average nucleotide identity values of 30.9% and 86.39%, respectively, confirming that the isolate represents a novel species within the genus. Comparative pan-genome analysis revealed an open pan-genome comprising 19,613 gene clusters, including 1,288 strain-specific genes. Phenotypic, physiological, and chemotaxonomic analyses further distinguished the isolate from closely related Paracoccus type strains. Genome mining using antiSMASH and KEGG pathway reconstruction identified key carotenoid biosynthesis genes (idi, crtE, crtB, crtI, crtY, crtZ, and crtW). The strain produced 67.93 ± 3.76 mg g⁻¹ dry biomass of crude pigment, and UHPLC-APCI-Orbitrap MS/MS confirmed the production of astaxanthin, zeaxanthin, canthaxanthin, retinal, and several apo-carotenoid derivatives. Based on comprehensive phenotypic, chemotaxonomic, phylogenetic, genomic, and metabolomic evidence, strain Z12 is proposed as Paracoccus niotae sp. nov. NIOT.M2S5SZ12ᵀ under the SeqCode framework. These findings establish Paracoccus niotae as a promising marine microbial resource for sustainable carotenoid production and biotechnology.
Indexed as
Identifiers
42801408What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.