Evidence map›Paper›PMID 42801532›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72

Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xingling He *State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0009-0009-4865-4584
Sijing Li *State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Jiahui Chen *State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Liyu Lin *State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0009-0005-7600-394X
Xinyu Li *State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0001-5360-7154
Xiaojiao ZhangState Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Yihui ZhangState Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Xingling ChenState Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Jinjian GuoThe Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Zhongqi YangState Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Lu LuState Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0002-9457-0164
Shihao NiState Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Funding

Fujian Province Young Scientific and Technological Talent Development Program 2026350685General Program of Natural Science Fund from Guangdong Provincial Basic and Applied Basic Research Foundation 2026A1515012409Guangdong Medical Science and Technology Research Fund B2025119Guangzhou Key R&D Program 2024B03J1298Guangzhou University of Chinese Medicine GZY2025GB0104Inheritance Studio of Guangdong Provincial Famous TCM PhysicianKey National Research and Development Program Project 2025YFC3507902National Natural Science Foundation of China 82505436State Key Laboratory of Traditional Chinese MedicineSyndrome "Open bidding for selecting the best candidates" Key Research Projects SKLKY2025C0013Young Talent Support Project of Guangzhou Association for Science and Technology QT-2025-037
6 · The paper itself

Abstract

Atherosclerotic cardiovascular disease (ASCVD) remains the leading global cause of mortality, with substantial residual inflammatory risk persisting despite statin therapy. We identify a c-Rel-driven CD72

Indexed as

atherosclerosisCD72hi macrophagesCXCL12‐CXCR4 axisendothelial pyroptosisIlexoside Kvascular inflammation

Identifiers

PMID42801532
PMCPMC13616409

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.