Evidence map›Paper›PMID 42802250›Full record

ArticleGeroScience2026

A 9-year longitudinal investigation into physiological aging in highly active older adults.

Amir S Fathi, Thomas Francis, Eloise Milbourn, Esme Newton, Leah Siegel, Suzanne Taylor, Niharika A Duggal, Janet M Lord, Norman R Lazarus, Ross D Pollock and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amir S FathiCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0000-0002-7517-2566
Thomas FrancisCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0000-0002-1021-8834
Eloise MilbournCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0009-0003-5028-3053
Esme NewtonCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0009-0008-8078-1316
Leah SiegelCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0009-0009-3079-8758
Suzanne TaylorCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0009-0004-6460-971X
Niharika A DuggalMRC-Versus Arthritis Centre for Musculoskeletal Ageing & Research & Department of Inflammation and Ageing, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0003-4459-4632
Janet M LordMRC-Versus Arthritis Centre for Musculoskeletal Ageing & Research & Department of Inflammation and Ageing, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0003-1030-6786
Norman R LazarusCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0000-0002-3519-5034
Ross D PollockCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK.ORCID http://orcid.org/0000-0002-3184-8253
Stephen D R HarridgeCentre for Human & Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, Guy's Campus, Shepherd's House, London, SE1 1UL, UK. s.harridge@kcl.ac.uk.ORCID http://orcid.org/0000-0002-8203-0769

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the impact of nine years of continued cycling exercise on physiological function in older exercisers, viewed as a model of inherent biological aging free from the negative effects of inactivity. A range of cardiorespiratory indices were measured, with peak oxygen consumption (V̇O

Indexed as

Cardiorespiratory functionExercisePhysiological aging

Identifiers

PMID42802250

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.