Evidence map›Paper›PMID 42808524›Full record

ReviewMolecular ecology2026

Polyphenism Through RNA Chemical Modifications.

Ralf Schneider, Ehsan Pashay Ahi

Abstract readReview
In one paragraph

Review in Molecular ecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ralf SchneiderMarine Evolutionary Biology, Zoological Institute, Am Botanischen Garten 1-9, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0001-6015-7219
Ehsan Pashay AhiFaculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-6528-1187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenism, the capacity of a single genotype to produce discrete phenotypes in response to environmental cues, has long served as a model for understanding developmental plasticity. While classical studies have highlighted hormonal signalling and transcription-factor-driven gene regulatory networks that mediate these environmentally induced shifts, recent advances have uncovered a new layer of gene regulation through chemical modifications of RNA molecules. These RNA modifications, collectively known as epitranscriptomic marks, have been shown to respond to environmental signals and modulate RNA fate. Despite their regulatory potential, their involvement in polyphenic systems remains largely unexplored. Here, we synthesize evidence suggesting that RNA modifications may form a dynamic, context-sensitive interface linking environmental inputs to phenotypic expression and developmental commitment in polyphenic systems.

Indexed as

PhenotypeRNAAnimalsEpigenesis, GeneticEpitranscriptomeEpitranscriptomicsGene Expression RegulationGene Regulatory NetworksGenotypeRNAenvironmental regulationEpitranscriptomicsphenotypic plasticityPolyphenismRNA modifications

Identifiers

PMID42808524
PMCPMC13621574

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.