ArticleJournal of inflammation research2026
CircRNA Profiling Identifies hsa_circRNA_003201 Associated with a Predicted NLRX1-Related Regulatory Network in an Acne-Associated Inflammatory Sebocyte Model.
Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Background: Circular RNAs (circRNAs) are a class of non-coding RNAs that regulate gene expression and have been implicated in inflammatory skin diseases. Sebocytes play a central role in acne pathogenesis by regulating sebum production and inflammatory responses. However, the roles of circRNAs in sebocytes during acne remain poorly understood. This study aimed to characterize circRNA expression profiles and explore their potential functions in acne-associated inflammation. Methods: Human SZ95 sebocytes were stimulated with formalin-killed Results: Sixteen differentially expressed circRNAs were identified in f- Conclusion: This study provides a circRNA expression profile in an acne-like inflammatory sebocyte model and identifies hsa_circRNA_003201 as a candidate circRNA associated with acne-associated inflammation. The findings suggest a potential circRNA-miRNA-mRNA regulatory network involving NLRX1 and provide new insights into acne inflammatory mechanisms. Further functional studies are required to validate the proposed regulatory relationships.
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