ReviewOpen medicine (Warsaw, Poland)2026
Translating microbial knowledge into clinical biofilm therapies.
Review in Open medicine (Warsaw, Poland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms are highly organized microbial communities that adhere to living or nonliving surfaces and are enclosed in a self-produced extracellular matrix. Their tolerance against antimicrobial agents and host defenses makes them a major challenge across clinical, industrial, and environmental fields. This review offers an in-depth analysis of biofilm formation, structure, and dispersal mechanisms, highlighting the genetic and molecular regulators that underlie their development. This review also provides extensive details of advanced and investigative strategies for biofilm eradication, including antibody-based approaches, photodynamic therapy, nanotechnology-driven solutions, surface modification of biomaterials, biological and phage-based approaches, the integration of smart and responsive systems, and host immune modulation methods. By integrating recent advances in imaging, experimental modeling, therapeutic innovations, artificial intelligence, and machine learning models, this work highlights not only the complexity of biofilm biology but also the research and development prospects for effective intervention tools. Finally, this review discusses major translational challenges associated with moving antibiofilm strategies from laboratory research to clinical and device-related applications. This review also proposes practical guidelines to overcome these challenges. Overall, the review highlights the requirements for interdisciplinary collaboration across microbiology, materials science, clinical medicine, and regulatory frameworks. Unlike traditional descriptive reviews, this review adopts a decision-oriented framework, providing clear research guidance for researchers.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.